Real-time imaging of nanoparticles (green) coated with polyethylene-glycol (PEG), a hydrophilic, non-toxic polymer, penetrate within normal rodent brain. Without the PEG coating, negatively charged, hydrophobic particles (red) of a similar size do not penetrate.
Credit: Elizabeth Nance, Kurt Sailor, Graeme Woodworth.
Source: Coated nanoparticles move easily into brain tissue, The blood brain barrier (working group) at Johns Hopkins University.

Real-time imaging of nanoparticles (green) coated with polyethylene-glycol (PEG), a hydrophilic, non-toxic polymer, penetrate within normal rodent brain. Without the PEG coating, negatively charged, hydrophobic particles (red) of a similar size do not penetrate.

Credit: Elizabeth Nance, Kurt Sailor, Graeme Woodworth.

Source: Coated nanoparticles move easily into brain tissueThe blood brain barrier (working group) at Johns Hopkins University.